YU-101( YU101 | YU 101 )

Catalog No. M13763 CAS No. 254888-42-1

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

YU-101
Note

Research use only, not for human use.
Brief Description

A potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.
Description

A potent, specific proteasome β5 subunit inhibitor with IC50 of 0.26 uM, 7.3 and 17.3-fold selectivity over β2i and β1i subunit, respecitvely.
In Vitro

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In Vivo

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Synonyms

YU101 | YU 101
Pathway

Proteasome/Ubiquitin
Target

Proteasome
Recptor

Proteasome
Research Area

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Indication

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CAS Number

254888-42-1
Formula Weight

634.818
Molecular Formula

C36H50N4O6
Purity

>98% (HPLC)
Solubility

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SMILES

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Chemical Name

(S)-2-((S)-2-acetamido-4-phenylbutanamido)-4-methyl-N-((S)-1-(((S)-4-methyl-1-((R)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-1-oxo-3-phenylpropan-2-yl)pentanamide

1. Screen M, et al. J Biol Chem. 2010 Dec 17;285(51):40125-34.

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