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HSP27 inhibitor J2
CAS No. 2133499-85-9
HSP27 inhibitor J2( —— )
Catalog No. M13399 CAS No. 2133499-85-9
HSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 455 | In Stock |
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| 2MG | 185 | In Stock |
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| 5MG | 312 | In Stock |
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| 10MG | 472 | In Stock |
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| 25MG | 753 | In Stock |
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| 50MG | 1042 | In Stock |
|
| 100MG | 1386 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHSP27 inhibitor J2
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NoteResearch use only, not for human use.
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Brief DescriptionHSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27.
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DescriptionHSP27 inhibitor J2 is a small molecule functional inhibitor of Hsp27, induces significant abnormal HSP27 dimer formation in cancer cells; enhances cancer cell sensitization with cisplatin, cisplatin-induced lung cancer cell growth inhibition in vitro; significantly inhibits immune cell infiltration in lung tissue, attenuates radiation-induced pulmonary inflammation in mice.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetHSP
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RecptorHSP
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Research Area——
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Indication——
Chemical Information
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CAS Number2133499-85-9
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Formula Weight264.295
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Molecular FormulaC13H12O4S
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20 mg/mL (75.67 mM)
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SMILESO=C1C=C(C)OC2=C1C(O)=CC(OCC3SC3)=C2
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Chemical Name5-hydroxy-2-methyl-7-(thiiran-2-ylmethoxy)-4H-chromen-4-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Kim JY, et al. Sci Rep. 2018 Mar 8;8(1):4189.
2. Hwang SY, et al. Eur J Med Chem. 2017 Oct 20;139:892-900.
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