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DAPT
CAS No. 208255-80-5
DAPT ( GSI-IX )
Catalog No. M13243 CAS No. 208255-80-5
DAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 2MG | 32 | In Stock |
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| 5MG | 50 | In Stock |
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| 10MG | 86 | In Stock |
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| 25MG | 160 | In Stock |
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| 50MG | 272 | In Stock |
|
| 100MG | 369 | In Stock |
|
| 200MG | 507 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDAPT
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NoteResearch use only, not for human use.
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Brief DescriptionDAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.
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DescriptionDAPT (GSI-IX) is a novel γ-secretase inhibitor, which inhibits Aβ production with IC50 of 20 nM in HEK 293 cells.
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In VitroDAPT (GMP) (9 d) induces human induced pluripotent stem cells develop into expandable myoblasts.DAPT (GMP) (13 d) induces human pluripotent stem cells (hPSCs) develop into functional neurons.
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In Vivo——
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SynonymsGSI-IX
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PathwayNeuroscience
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TargetGamma-secretase
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Recptorγ secretase(Aβ)
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number208255-80-5
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Formula Weight432.46
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Molecular FormulaC23H26F2N2O4
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Purity>98% (HPLC)
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SolubilityEthanol: 50 mg/mL (115.61 mM); DMSO: 86 mg/mL (198.86 mM)
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SMILESO=C(OC(C)(C)C)[C@H](C1=CC=CC=C1)NC([C@H](C)NC(CC2=CC(F)=CC(F)=C2)=O)=O
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Chemical Nametert-butyl (S)-2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Dovey HF, et al. J Neurochem. 2001, 76(1), 173-18
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