Cart
sales@molnova.com
ACO1
CAS No. 2065198-79-8
ACO1( ACO 1 )
Catalog No. M13211 CAS No. 2065198-79-8
ACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameACO1
-
NoteResearch use only, not for human use.
-
Brief DescriptionACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM.
-
DescriptionACO1 is a potent, selective Grp94 inhibitor with IC50 of 0.44 uM, displays >200-fold selectivity against other Hsp90 isoforms; exhibits a significant decrease in mutatnt myocilin I477N levels at 30 uM in tetracycline inducible HEK cells; inhibits the migration of MDA-MB-231 and PC-3 MM-2 at 10 uM and 5 uM,respectively.
-
In Vitro——
-
In Vivo——
-
SynonymsACO 1
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2065198-79-8
-
Formula Weight405.498
-
Molecular FormulaC24H27N3O3
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name4-(2-(2-hydroxybenzyl)-1H-pyrrol-1-yl)-2-(((1r,4r)-4-hydroxycyclohexyl)amino)benzamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mishra SJ, et al. ACS Chem Biol. 2017 Jan 20;12(1):244-253.
molnova catalog
related products
-
Col 003
Col 003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM.
-
HS-131
HS-131 is an imaging probe of Hsp90 activity by linking it to a near-infrared (nIR) dye.
-
YZ129
YZ129 (YZ-129) is a small molecule inhibitor of HSP90-Calcineurin-NFAT pathway, suppresses TG-induced NFAT nuclear translocation in HeLa cellswith IC50 of 820 nM.
