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BI 7189
CAS No. 1883429-32-0
BI 7189( BI7189 )
Catalog No. M12928 CAS No. 1883429-32-0
BI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameBI 7189
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NoteResearch use only, not for human use.
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Brief DescriptionBI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9.
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DescriptionBI 7189 is a highly selective bromodomains of BRD9 and BRD7 inhibitor with IC50<50 nM for BRD9, displays >1,000 fold selectivity over the bromodomains of BRD4; suppresses the proliferation of AML cells.
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In Vitro——
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In Vivo——
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SynonymsBI7189
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research Area——
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Indication——
Chemical Information
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CAS Number1883429-32-0
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Formula Weight330.428
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Molecular FormulaC19H26N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name5-[4-[(dimethylamino)methyl]-3,5-dimethoxyphenyl]-1,3,6-trimethylpyridin-2-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Hohmann AF, et al. Nat Chem Biol. 2016 Sep;12(9):672-9.
2. Pérez-Salvia M, et al. Epigenetics. 2017 May 4;12(5):323-339.
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