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(R)-(-)-JQ1 Enantiomer
CAS No. 1268524-71-5
(R)-(-)-JQ1 Enantiomer( —— )
Catalog No. M11127 CAS No. 1268524-71-5
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 46 | In Stock |
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| 5MG | 40 | In Stock |
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| 10MG | 57 | In Stock |
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| 25MG | 93 | In Stock |
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| 50MG | 133 | In Stock |
|
| 100MG | 198 | In Stock |
|
| 200MG | 295 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(R)-(-)-JQ1 Enantiomer
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NoteResearch use only, not for human use.
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Brief Description(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor.
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Description(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, (+)-JQ-1 is a potent, specific BET bromodomain BRD4 inhibitor, but (-)-JQ1 has no activity.
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In Vitro(R)-(-)-JQ1 Enantiomer shows no significant interaction with any bromodomain. Besides, (R)-(-)-JQ1 Enantiomer is comparatively inactive in nuclear protein in testis (NUT) midline carcinoma (NMC).
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In Vivo——
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Synonyms——
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PathwayChromatin/Epigenetic
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TargetBromodomain
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RecptorBromodomain
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1268524-71-5
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Formula Weight456.9882
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Molecular FormulaC23H25ClN4O2S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCC1=C(SC2=C1C(=NC(C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C
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Chemical Name6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid, 4-(4-chlorophenyl)-2,3,9-trimethyl-, 1,1-dimethylethyl ester, (6R)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Filippakopoulos P, et al. Nature. 2010 Dec 23;468(7327):1067-73.
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