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MM-206
CAS No. 1809581-87-0
MM-206( MM206 | MM 206 )
Catalog No. M12775 CAS No. 1809581-87-0
A novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameMM-206
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NoteResearch use only, not for human use.
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Brief DescriptionA novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM.
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DescriptionA novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD); also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM,
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In Vitro——
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In Vivo——
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SynonymsMM206 | MM 206
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PathwayJAK/STAT Signaling
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TargetSTAT
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RecptorSTAT
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Research Area——
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Indication——
Chemical Information
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CAS Number1809581-87-0
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Formula Weight497.454
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Molecular FormulaC22H12F5NO3S2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=S(C1=C(F)C(F)=C(F)C(F)=C1F)(NC2=C3C=CC=CC3=C(O)C(SC4=CC=CC=C4)=C2)=O
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Chemical Name2,3,4,5,6-pentafluoro-N-(4-hydroxy-3-(phenylthio)naphthalen-1-yl)benzenesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Minus MB, et al. Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13085-9.
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