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KRAS G12C inhibitor 1

CAS No. 1698023-15-2

KRAS G12C inhibitor 1( —— )

Catalog No. M12589 CAS No. 1698023-15-2

A potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.

Purity : >98% (HPLC)

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Biological Information

Product Name

KRAS G12C inhibitor 1
Note

Research use only, not for human use.
Brief Description

A potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
Description

A potent, selective, covalent KRAS G12C inhibitor that selectively inhibit KRAS G12C-dependent signaling and cancer cell growth at sub-micromolar concentrations.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

MAPK/ERK Signaling
Target

Ras
Recptor

Ras
Research Area

——
Indication

——

Chemical Information

CAS Number

1698023-15-2
Formula Weight

396.85
Molecular Formula

C21H18ClFN4O
Purity

>98% (HPLC)
Solubility

——
SMILES

——
Chemical Name

1-(4-(6-chloro-7-(2-fluorophenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Zeng M, et al. Cell Chem Biol. 2017 Aug 17;24(8):1005-1016.e3.

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