Linezolid( PNU 100766 )

Catalog No. M12529 CAS No. 165800-03-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Linezolid
Note

Research use only, not for human use.
Brief Description

Linezolid is a synthetic antibiotic, the first of the oxazolidinone class.
Description

Linezolid is a synthetic antibiotic, the first of the oxazolidinone class, used for the treatment of infections caused by multi-resistant bacteria including streptococcus and methicillin-resistant Staphylococcus aureus (MRSA). The drug works by inhibiting the initiation of bacterial protein synthesis. (In Vitro):Linezolid (PNU-100766) prevents the synthesis of bacterial protein via binding to rRNA on both the 30S and 50S ribosomal subunits.
In Vitro

Linezolid (PNU-100766) prevents the synthesis of bacterial protein via binding to rRNA on both the 30S and 50S ribosomal subunits.
In Vivo

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Synonyms

PNU 100766
Pathway

Metabolic Enzyme/Protease
Target

MAO
Recptor

AOA| AOB
Research Area

Infection
Indication

——

CAS Number

165800-03-3
Formula Weight

337.35
Molecular Formula

C16H20FN3O4
Purity

>98% (HPLC)
Solubility

Ethanol: 8 mg/mL (23.71 mM); DMSO: 67 mg/mL (198.6 mM)
SMILES

CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCOCC3)F
Chemical Name

N-[[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

1.Stevens DL, et al. Expert Rev Anti Infect Ther. 2004 Feb;2(1):51-9.

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