Ampalex

CAS No. 154235-83-3

Ampalex( Ampalex | BDP-12 | Benzoyl-Piperidine-12 )

Catalog No. M12187 CAS No. 154235-83-3

Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
10MG 28 In Stock
25MG 36 In Stock
50MG 55 In Stock
100MG 71 In Stock
200MG 126 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Ampalex
  • Note
    Research use only, not for human use.
  • Brief Description
    Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease.
  • Description
    Ampalex (Ampakine CX516; CX516; BDP 12) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).(In Vitro):.(In Vivo):The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.).
  • In Vitro
    ——
  • In Vivo
    The specific extradimensional deficits produced by sub-chronic or early postnatal postnatal phencyclidine treatment were significantly attenuated by CX516 (10, and 20 mg/kg, s.c.). Animal Model:Male Lister Hooded rats (56-63 postnatal day)Dosage:5, 10, 20, and 40 mg/kg Administration:Subcutaneously Result:Two doses (10 and 20 mg/kg) were highly significant in improving the extradimensional shift deficit induced by either treatment regimes. Two doses (5 and 40 mg/kg) was ineffective at reversing the extradimensional impairment induced by the sub-chronic postnatal phencyclidine treatment regime.
  • Synonyms
    Ampalex | BDP-12 | Benzoyl-Piperidine-12
  • Pathway
    Neuroscience
  • Target
    GluR
  • Recptor
    AMPA
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    154235-83-3
  • Formula Weight
    241.29
  • Molecular Formula
    C14H15N3O
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 40 mg/mL
  • SMILES
    O=C(N1CCCCC1)C2=CC=C3N=CC=NC3=C2
  • Chemical Name
    1-(quinoxalin-6-ylcarbonyl)piperidine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Broberg BV, et al. Psychopharmacology (Berl). 2009 Nov;206(4):631-40.
molnova catalog
related products
  • DNQX

    DNQX is a competitive non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors respectively).

  • ML 254

    ML254 competitively interacts with the MPEP allosteric binding site. ML254 is highly selective for mGlu5 versus other mGlu receptors, has a clean ancillary Ricerca profile, and suitable dystrophia myotonica protein kinase (DMPK) properties for systemic dosing in rodents.

  • KML29

    KML29 is highly selective and effective monoacylglycerol lipase (MAGL) inhibitor.