Cart
sales@molnova.com
PU-WS13
CAS No. 1454619-14-7
PU-WS13( PU-WS-13 )
Catalog No. M11960 CAS No. 1454619-14-7
A potent and selective Grp94 inhibitor with Ic50 of 0.22 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 50MG | 659 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePU-WS13
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent and selective Grp94 inhibitor with Ic50 of 0.22 uM.
-
DescriptionA potent and selective Grp94 inhibitor with Ic50 of 0.22 uM; shows >35 fold selectivity over other four HSP90 paralogs, Hsp90α, Hsp90β and Trap-1 (IC50> 7 uM).
-
In Vitro——
-
In Vivo——
-
SynonymsPU-WS-13
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetHSP
-
RecptorHSP
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1454619-14-7
-
Formula Weight411.3519
-
Molecular FormulaC17H20Cl2N6S
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 40 mg/mL
-
SMILESNC1=C2N=C(SC3=CC(Cl)=CC(Cl)=C3)N(CCCNC(C)C)C2=NC=N1
-
Chemical Name9H-Purine-9-propanamine, 6-amino-8-[(3,5-dichlorophenyl)thio]-N-(1-methylethyl)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Patel PD, et al. Nat Chem Biol. 2013 Nov;9(11):677-84.
molnova catalog
related products
-
2',4'-DIHYDROXYCHALC...
2',4'-Dihydroxychalcone as a compound with Hsp90 inhibitory and antifungal effectsIn the presence of 2',4'-DHC (8 g/mL), radial growth of Aspergillus fumigatus was inhibited 20% compared to the control, and green pigmentation was completely blocked.
-
VER-155008
A potent Hsp70 family (Hsc70/Hsp7/Grp78) inhibitor with Kd of 80 nM for Grp78.
-
HS-72
HS-72 is an allosteric, selective, cell-permeable inhibitor of inducible Hsp70 (Hsp70i or Hsp72).
