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PR-893
CAS No. 1426305-23-8
PR-893( PR 893 | PR893 | CPSI )
Catalog No. M11800 CAS No. 1426305-23-8
A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePR-893
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM.
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DescriptionA potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
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In Vitro——
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In Vivo——
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SynonymsPR 893 | PR893 | CPSI
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PathwayProteasome/Ubiquitin
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TargetProteasome
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RecptorProteasome
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Research Area——
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Indication——
Chemical Information
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CAS Number1426305-23-8
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Formula Weight478.546
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Molecular FormulaC23H34N4O7
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical NameN-((S)-1-(((S)-1-cyclopropyl-2-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-3-methoxy-1-oxopropan-2-yl)-5-methylisoxazole-3-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Parlati F, et al. Blood. 2009 Oct 15;114(16):3439-47.
2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
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