Cart
sales@molnova.com
PR-893
CAS No. 1426305-23-8
PR-893( PR 893 | PR893 | CPSI )
Catalog No. M11800 CAS No. 1426305-23-8
A potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePR-893
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM.
-
DescriptionA potent, specific immunoproteasome β5 subunit inhibitor with IC50 of 17 nM, 21-fold and 13-fold selectivity for β5 over LMP7 and LMP2 subunits, respecitvely.
-
In Vitro——
-
In Vivo——
-
SynonymsPR 893 | PR893 | CPSI
-
PathwayProteasome/Ubiquitin
-
TargetProteasome
-
RecptorProteasome
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1426305-23-8
-
Formula Weight478.546
-
Molecular FormulaC23H34N4O7
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical NameN-((S)-1-(((S)-1-cyclopropyl-2-(((S)-4-methyl-1-((S)-2-methyloxiran-2-yl)-1-oxopentan-2-yl)amino)-2-oxoethyl)amino)-3-methoxy-1-oxopropan-2-yl)-5-methylisoxazole-3-carboxamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Parlati F, et al. Blood. 2009 Oct 15;114(16):3439-47.
2. de Bruin G, et al. J Med Chem. 2014 Jul 24;57(14):6197-209.
molnova catalog
related products
-
KDM5-inhibitor
KDM5 inhibitor.
-
(1S,2S)-Bortezomib
(1S,2S)-Bortezomib is an enantiomer of Bortezomib. Bortezomib is a reversible and selective inhibitor of the proteasome with a Ki of 0.6 nM for 20S proteasome.
-
Delanzomib
A potent, orally active proteasome inhibitor with IC50 of 3.8 nM against chymotrypsin-like proteasome activity.
