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ABT-751
CAS No. 141430-65-1
ABT-751( ABT751 | ABT 751 | E7010 | E-7010 | E 7010 )
Catalog No. M11717 CAS No. 141430-65-1
ABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 43 | In Stock |
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| 5MG | 39 | In Stock |
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| 10MG | 58 | In Stock |
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| 25MG | 118 | In Stock |
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| 50MG | 169 | In Stock |
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| 100MG | 271 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameABT-751
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NoteResearch use only, not for human use.
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Brief DescriptionABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization.
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DescriptionABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL); shows good antitumor activity against various rodent tumors and human tumor xenografts, Lung Cancer Discontinued.
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In Vitro——
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In Vivo——
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SynonymsABT751 | ABT 751 | E7010 | E-7010 | E 7010
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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Recptormicrotubule
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Research AreaCancer
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IndicationLung Cancer
Chemical Information
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CAS Number141430-65-1
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Formula Weight371.4
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Molecular FormulaC18H17N3O4S
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 48 mg/mL
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SMILESCOC1=CC=C(C=C1)S(=O)(=O)NC1=C(NC2=CC=C(O)C=C2)N=CC=C1
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Chemical NameBenzenesulfonamide, N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Koyanagi N, et al. Cancer Res. 1994 Apr 1;54(7):1702-6.
2. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13.
3. Segreti JA, et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81.
4. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13.
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