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ABT-751

CAS No. 141430-65-1

ABT-751( ABT751 | ABT 751 | E7010 | E-7010 | E 7010 )

Catalog No. M11717 CAS No. 141430-65-1

ABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 43 In Stock
5MG 39 In Stock
10MG 58 In Stock
25MG 118 In Stock
50MG 169 In Stock
100MG 271 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    ABT-751
  • Note
    Research use only, not for human use.
  • Brief Description
    ABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization.
  • Description
    ABT-751 (E-7010) is an orally active antimitotic agent that inhibits tubulin polymerization, exhibits consistent growth-inhibitory activities against a panel of human tumor cell lines (IC50=0.06-0.8 ug/mL); shows good antitumor activity against various rodent tumors and human tumor xenografts, Lung Cancer Discontinued.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ABT751 | ABT 751 | E7010 | E-7010 | E 7010
  • Pathway
    Cytoskeleton/Cell Adhesion Molecules
  • Target
    Microtubule/Tubulin
  • Recptor
    microtubule
  • Research Area
    Cancer
  • Indication
    Lung Cancer

Chemical Information

  • CAS Number
    141430-65-1
  • Formula Weight
    371.4
  • Molecular Formula
    C18H17N3O4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 48 mg/mL
  • SMILES
    COC1=CC=C(C=C1)S(=O)(=O)NC1=C(NC2=CC=C(O)C=C2)N=CC=C1
  • Chemical Name
    Benzenesulfonamide, N-[2-[(4-hydroxyphenyl)amino]-3-pyridinyl]-4-methoxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Koyanagi N, et al. Cancer Res. 1994 Apr 1;54(7):1702-6. 2. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13. 3. Segreti JA, et al. Cancer Chemother Pharmacol. 2004 Sep;54(3):273-81. 4. Yoshimatsu K, et al. Cancer Res. 1997 Aug 1;57(15):3208-13.
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