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DZ-2384
CAS No. 1403850-91-8
DZ-2384( DZ2384 )
Catalog No. M11690 CAS No. 1403850-91-8
DZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameDZ-2384
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NoteResearch use only, not for human use.
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Brief DescriptionDZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types.
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DescriptionDZ-2384 (DZ2384) is a microtubule-targeting agent, exhibits potent antitumor activity in models of multiple cancer types; binds the vinca domain of tubulin, DZ-2384 has potent antitumor activity as a single agent and in combination with gemcitabine both in vitro and in vivo, enhances gemcitabine activity in mouse models of pancreatic cancer.
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In Vitro——
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In Vivo——
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SynonymsDZ2384
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetMicrotubule/Tubulin
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RecptorMicrotubule/Tubulin
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Research Area——
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Indication——
Chemical Information
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CAS Number1403850-91-8
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Formula Weight645.677
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Molecular FormulaC34H36FN5O7
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Purity>98% (HPLC)
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Solubility——
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SMILESCC(C)C(C(=O)NC1CC2=CC3=C(C=C2)OC4C3(C5=C(N4)C=CC(=C5)F)C6=C(N=C(O6)C(NC1=O)C(C)(C)C)C7=NC(=CO7)CO)O
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Chemical Name(S)-N-((15aR,110bS,3S,6S)-3-(tert-butyl)-19-fluoro-24-(4-(hydroxymethyl)oxazol-2-yl)-5-oxo-15a,110b-dihydro-16H-4-aza-1(10b,2)-benzofuro[2,3-b]indola-2(5,2)-oxazolacycloheptaphane-6-yl)-2-hydroxy-3-methylbutanamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Ding H, et al. Angew Chem Int Ed Engl. 2015 Apr 13;54(16):4818-22.
2. Wieczorek M, et al. Sci Transl Med. 2016 Nov 16;8(365):365ra159.
3. Bernier C, et al. Anticancer Drugs. 2018 Jun 22. doi: 10.1097/CAD.0000000000000653.
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