Seocalcitol( EB-1089 )

Catalog No. M11377 CAS No. 134404-52-7

Seocalcitol is vitamin D3 analogue with potential antineoplastic activity.

Purity : >98% (HPLC)

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Biological Information

Product Name

Seocalcitol
Note

Research use only, not for human use.
Brief Description

Seocalcitol is vitamin D3 analogue with potential antineoplastic activity.
Description

Seocalcitol is vitamin D3 analogue with potential antineoplastic activity. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide expressed in normal vitamin D responsive tissues, but also overexpressed in certain cancers including hepatocellular carcinoma and pancreatic cancer.Liver Cancer Phase 2 Clinical.
In Vitro

——
In Vivo

——
Synonyms

EB-1089
Pathway

Metabolic Enzyme/Protease
Target

Vitamin
Recptor

Vitamin
Research Area

Cancer
Indication

Liver Cancer

Chemical Information

CAS Number

134404-52-7
Formula Weight

454.6844
Molecular Formula

C30H46O3
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CCC(CC)(C=CC=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)O
Chemical Name

1,3-Cyclohexanediol, 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,2E,4E)-6-ethyl-6-hydroxy-1-methyl-2,4-octadien-1-yl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1R,3S,5Z)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Wang K, et al. Histopathology. 2015 Sep;67(3):386-97. 2. Sharma K, et al. Autophagy. 2014;10(12):2346-61. 3. Bhatia V, et al. Mol Cancer Ther. 2009 Jul;8(7):1787-98.

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