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SRTCX1003
CAS No. 1203480-93-6
SRTCX1003( SRTCX-1003 )
Catalog No. M10743 CAS No. 1203480-93-6
SRTCX1003 (SRTCX-1003) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.61 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameSRTCX1003
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NoteResearch use only, not for human use.
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Brief DescriptionSRTCX1003 (SRTCX-1003) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.61 uM.
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DescriptionSRTCX1003 (SRTCX-1003) is a small molecule activator of SIRT1 (STAC) with EC1.5 of 0.61 uM, enhances deacetylation of cellular p65 protein with IC50 of 1.42 uM in cellular p65 acetylation assay; suppresses TNFα-induced NF-κB transcriptional activation and reduction of LPS-stimulated TNFα secretion in a SIRT1-dependent manner, decreases the production of the proinflammatory cytokines TNFα and IL-12 in acute mouse model of LPS-induced inflammation.
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In Vitro——
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In Vivo——
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SynonymsSRTCX-1003
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PathwayChromatin/Epigenetic
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TargetSirtuin
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RecptorSirtuin
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Research Area——
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Indication——
Chemical Information
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CAS Number1203480-93-6
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Formula Weight449.529
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Molecular FormulaC23H23N5O3S
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=C(C=CC(=C1)C=CC(=O)C2=CC=C(C=C2)Cl)O.O
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Chemical Name2-(3-(2-morpholinoethoxy)phenyl)-N-(thiazol-2-yl)-1H-benzo[d]imidazole-7-carboxamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Yang H, et al. PLoS One. 2012;7(9):e46364.
2. Kim SY, et al. PLoS One. 2015 Jul 15;10(7):e0133448.
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