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Ixazomib Citrate
CAS No. 1201902-80-8
Ixazomib Citrate( Ixazomib Citrate )
Catalog No. M10726 CAS No. 1201902-80-8
MLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 39 | In Stock |
|
| 10MG | 55 | In Stock |
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| 25MG | 87 | In Stock |
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| 50MG | 120 | In Stock |
|
| 100MG | 203 | In Stock |
|
| 200MG | 302 | In Stock |
|
| 500MG | 507 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameIxazomib Citrate
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NoteResearch use only, not for human use.
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Brief DescriptionMLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma.
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DescriptionMLN9708 immediately hydrolyzed to MLN2238, the biologically active form, on exposure to aqueous solutions or plasma. MLN2238 inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with IC50/Ki of 3.4 nM/0.93 nM, less potent to β1 and little activity to β2. Phase 3.
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In Vitro——
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In Vivo——
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SynonymsIxazomib Citrate
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PathwayProteasome/Ubiquitin
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TargetProteasome
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Recptor20S proteasome| 20S proteasome
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1201902-80-8
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Formula Weight517.12
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Molecular FormulaC20H23BCl2N2O9
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mg/mL (193.37 mM)
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SMILESB1(OC(=O)CC(O1)(CC(=O)O)C(=O)O)[C@H](CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kupperman E, et al. Y Res, 2010, 70(5), 1970-80.
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