Cart
sales@molnova.com
AVN-322 free base
CAS No. 1194574-33-8
AVN-322 free base( AVN 323 free base )
Catalog No. M10683 CAS No. 1194574-33-8
A highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 459 | In Stock |
|
| 10MG | 657 | In Stock |
|
| 25MG | 1026 | In Stock |
|
| 50MG | 1386 | In Stock |
|
| 100MG | 1832 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAVN-322 free base
-
NoteResearch use only, not for human use.
-
Brief DescriptionA highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia.
-
DescriptionA highly selective, potent, BBB penetrant and orally bioavailable 5-HT6R antagonist for the treatment of neurological disorders such as AD and schizophrenia; significantly restores both scopolamine- and MK-801-induced cognitive dysfunction and demonstrates antipsychotic potential.Alzheimer Disease Phase 2 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsAVN 323 free base
-
PathwayGPCR/G Protein
-
Target5-HT Receptor
-
Recptor5-HT Receptor
-
Research AreaNeurological Disease
-
IndicationAlzheimer Disease
Chemical Information
-
CAS Number1194574-33-8
-
Formula Weight357.432
-
Molecular FormulaC17H19N5O2S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCNC1=NN2C3=C(CN(CC3)C)C=NC2=C1S(=O)(=O)C4=CC=CC=C4
-
Chemical NameN,7-dimethyl-3-(phenylsulfonyl)-6,7,8,9-tetrahydropyrazolo[1,5-a]pyrido[3,4-e]pyrimidin-2-amine hydrochloride
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ivachtchenko AV, et al. Curr Alzheimer Res. 2017;14(3):268-294.
molnova catalog
related products
-
WAY-100635
A potent and selective 5-HT1A receptor antagonist; also acts as potent full agonist at the D4 receptor.
-
Liafensine
Liafensine(BMS-820836) is a novel and selective triple monoamine reuptake inhibitor with inhibitory effects on the reuptake of serotonin, norepinephrine, and dopamine for the study of major depressive disorder and central nervous system disorders.
-
MIN-117
A small molecule 5-HT1A and 5-HT2A receptor antagonist and inhibitor of serotonin and dopamine reuptake, also possess affinity for the α1A- and α1B-adrenergic receptors.
