Lecozotan HCl( —— )

Catalog No. M34311 CAS No. 433282-68-9

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Lecozotan HCl
Note

Research use only, not for human use.
Brief Description

Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties.
Description

Lecozotan HCl (SRA-333) is a potent and selective 5-HT antagonist that significantly enhances KCl-stimulated glutamate and acetylcholine release from the hippocampal dentate gyrus and has cognitive enhancing properties. Chronic administration of Lecozotan HCl did not induce 5-HT(1A) receptor tolerance or desensitization in a behavioral model demonstrating 5-HT(1A) receptor function.
In Vitro

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In Vivo

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Synonyms

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Pathway

GPCR/G Protein
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

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Indication

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CAS Number

433282-68-9
Formula Weight

520.02
Molecular Formula

C28H30ClN5O3
Purity

>98% (HPLC)
Solubility

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SMILES

[C@H](CN(C(=O)C1=CC=C(C#N)C=C1)C2=CC=CC=N2)(C)N3CCN(C4=C5C(=CC=C4)OCCO5)CC3.Cl
Chemical Name

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