Cart
sales@molnova.com
PI3Kγ inhibitor 1
CAS No. 1172118-03-4
PI3Kγ inhibitor 1( —— )
Catalog No. M10575 CAS No. 1172118-03-4
A potent PI3Kγ inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NamePI3Kγ inhibitor 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent PI3Kγ inhibitor.
-
DescriptionA potent PI3Kγ inhibitor.
-
In VitroIn Table 3, PI3Kγ inhibitor 1 (Compound 168) inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively. PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM.
-
In Vivo——
-
Synonyms——
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorPI3K
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1172118-03-4
-
Formula Weight586.6663
-
Molecular FormulaC32H26N8O2S
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCC1=C2C(=CC=C1)C=C(N(C2=O)C3=CC=CC=C3C)CN4C5=NC=NC(=C5C(=N4)C6=CC7=C(C=C6)N=C(S7)NC(=O)C)N
-
Chemical NameAcetamide, N-[6-[4-amino-1-[[1,2-dihydro-8-methyl-2-(2-methylphenyl)-1-oxo-3-isoquinolinyl]methyl]-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-2-benzothiazolyl]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Patent WO 2014004470.
molnova catalog
related products
-
Loureirin A
Loureirin A has an inhibitory effect on platelet activation perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen collagen-related peptide (CRP) ADP and thrombin.
-
CYH33
CYH33 (CYH-33) is a novel potent, PI3Kα-selective inhibitor with IC50 of 5.9 nM/598 nM/ 78.7 nM/225 nM aginst class I PI3K isoform α/β/δ/γ, respectively.
-
GDC-0980
GDC-0980 (Apitolisib, GNE 390, RG 7422) is a potent, selective, orally available class I PI3K/mTOR inhibitor with IC50 of 5 nM/27 nM/7 nM/14 nM for PI3Kα/β/δ/γ, inhibits mTOR inhibitor with Ki of 17 nM.
