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MK-0249
CAS No. 1167574-41-5
MK-0249( MK0249 )
Catalog No. M10571 CAS No. 1167574-41-5
MK-0249 is a novel potent, selective histamine H3 inverse agonist for the treatment of cognitive impairment with schizophrenia.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameMK-0249
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NoteResearch use only, not for human use.
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Brief DescriptionMK-0249 is a novel potent, selective histamine H3 inverse agonist for the treatment of cognitive impairment with schizophrenia.
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DescriptionMK-0249 is a novel potent, selective histamine H3 inverse agonist for the treatment of cognitive impairment with schizophrenia.Sleep Disorder Phase 1 Discontinued
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In Vitro——
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In Vivo——
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SynonymsMK0249
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorHistamine Receptor
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Research AreaNeurological Disease
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IndicationSleep Disorder
Chemical Information
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CAS Number1167574-41-5
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Formula Weight431.459
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Molecular FormulaC23H24F3N3O2
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C1N(C2=CC=C(OCCCN3CCCC3)C=C2)C(C)=NC4=C1C(C(F)(F)F)=CC=C4
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Chemical Name2-methyl-3-(4-(3-(pyrrolidin-1-yl)propoxy)phenyl)-5-(trifluoromethyl)quinazolin-4(3H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Brioni JD, et al. J Pharmacol Exp Ther. 2011 Jan;336(1):38-46.
2. James LM, et al. Psychopharmacology (Berl). 2011 Jun;215(4):643-53.
3. Zoethout RW, et al. J Psychopharmacol. 2012 Feb;26(2):292-302.
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