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SPK-601
CAS No. 1096687-52-3
SPK-601( LMV-601 | SPK-0601 )
Catalog No. M10375 CAS No. 1096687-52-3
A potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor; shows antiviral activity against herpes simplex virus (HSV).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 215 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameSPK-601
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NoteResearch use only, not for human use.
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Brief DescriptionA potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor; shows antiviral activity against herpes simplex virus (HSV).
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DescriptionA potent phosphatidylcholine-specific phospholipase C (PC-PLC) inhibitor; shows antiviral activity against herpes simplex virus (HSV); a novel antimicrobial agent.HSV Infection Phase 1 Clinical.
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In VitroSPK-601 (72 hours; HPV-31 cells) displays a dose dependent inhibitory effect on cell growth (IC50 of 16 μg/mL), and inhibits HPV-31 specific RNA expression and DNA replication. Cell Viability Assay Cell Line:9E human papilloma virus (HPV)-31 infected cervical epithelial cells Concentration:Incubation Time:72 hours Result:A dose dependent inhibitory effect on cell growth.
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In Vivo——
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SynonymsLMV-601 | SPK-0601
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PathwayMetabolic Enzyme/Protease
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TargetPhospholipase
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RecptorPhospholipase
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Research AreaInfection
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IndicationHSV Infection
Chemical Information
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CAS Number1096687-52-3
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Formula Weight266.4645
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Molecular FormulaC11H15KOS2
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILES[S-]C(O[C@@H]1[C@@](C2)([H])[C@]3([H])CCCC3[C@@]2([H])C1)=S.[K+]
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Chemical NameCarbonodithioic acid, O-[(3aR,4R,5S,7R,7aR)-octahydro-4,7-methano-1H-inden-5-yl] ester, potassium salt (1:1), rel-(-)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Walker K. IDrugs. 2010 Nov;13(11):743-5.
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