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JZP-430

CAS No. 1672691-74-5

JZP-430( —— )

Catalog No. M23752 CAS No. 1672691-74-5

JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

JZP-430
Note

Research use only, not for human use.
Brief Description

JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM).
Description

JZP-430 is an effective, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) (IC50: 44 nM). It also shows ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

MAGL
Recptor

ABHD6
Research Area

——
Indication

——

Chemical Information

CAS Number

1672691-74-5
Formula Weight

354.47
Molecular Formula

C16H26N4O3S
Purity

>98% (HPLC)
Solubility

DMSO:90 mg/mL?(253.9 mM;?Need ultrasonic)
SMILES

CN(C1CCCCCCC1)C(Oc1nsnc1N1CCOCC1)=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10(2):253-65.

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