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JAB-3068
CAS No. 2169223-48-5
JAB-3068( —— )
Catalog No. M35136 CAS No. 2169223-48-5
JAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor exhibiting anticancer and antitumor properties, designed for research in breast, lung, and esophageal cancers.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 84 | In Stock |
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| 5MG | 123 | In Stock |
|
| 10MG | 188 | In Stock |
|
| 25MG | 348 | In Stock |
|
| 50MG | 523 | In Stock |
|
| 100MG | 716 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameJAB-3068
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NoteResearch use only, not for human use.
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Brief DescriptionJAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor exhibiting anticancer and antitumor properties, designed for research in breast, lung, and esophageal cancers.
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DescriptionJAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM.
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In VitroJAB-3068 (SHP2-IN-6) inhibits the proliferation of KYSE-520 cells with an IC50 of 2.17 μM.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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RecptorPhosphatase
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Research Area——
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Indication——
Chemical Information
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CAS Number2169223-48-5
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Formula Weight476.54
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Molecular FormulaC22H26F2N6O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESS(C1=C2C(N(C(C)=O)CC2(F)F)=CC=C1)C=3C(N)=NC(=CN3)N4CCC5(CC4)[C@H](N)COC5
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1.
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