HIF-2α-IN-2
CAS No. 1672666-82-8
HIF-2α-IN-2( —— )
Catalog No. M23751 CAS No. 1672666-82-8
HIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 205 | In Stock |
|
| 10MG | 282 | In Stock |
|
| 25MG | 489 | In Stock |
|
| 50MG | 705 | In Stock |
|
| 100MG | 981 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameHIF-2α-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionHIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).
-
DescriptionHIF-2α-IN-2 is a hypoxia-inducible factor (HIF-2α) inhibitor (IC50: 16 nM in scintillation proximity assay).
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetHIF/HIF Prolyl-hydroxylase
-
RecptorHIF-2α
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1672666-82-8
-
Formula Weight365.35
-
Molecular FormulaC17H13F2NO4S
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (273.71 mM; Need ultrasonic)
-
SMILESN#CC1=CC(OC2=CC=C(S(=O)(C)=O)C3=C2CC(F)C3O)=CC(F)=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
-
103D5R
103D5R is a small-molecule inhibitor of HIF-1α that displays an EC50 of 35 uM against hypoxia-induced alkaline phosphatase enzymatic reporter activity.
-
Naphthofluorescein
Naphthofluorescein (Naphthafluorescein) is a Mint3 inhibitor with potential antitumor and anti-inflammatory activities, inhibits the interaction between HIF-1 and Mint3, inhibits Mint3-dependent HIF-1 activity, and inhibits glycolytic activity in cancer cells and macrophages without showing significant in vitro cytotoxicity or in vivo side effects.
-
Vadadustat
Vadadustat (PG-1016548, AKB-6548)?is a novel, potent, orally active HIF-PH inhibitor in development for the treatment of anemia in both nondialysis-dependent (NDD) and dialysis-dependent CKD.
Cart
sales@molnova.com