Cart
sales@molnova.com
HIF1-IN-2
CAS No. 159915-87-4
HIF1-IN-2( —— )
Catalog No. M12293 CAS No. 159915-87-4
A potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHIF1-IN-2
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB.
-
DescriptionA potent, selective HIF-1 inhibitor with IC50 of 1.9 nM, with no signigicant inhibition on HSF and NF-κB; robustly induces PGK1 and Enolase 1 expression, also inhibit endogenous HIF-1 targets.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetHIF/HIF Prolyl-hydroxylase
-
RecptorHIF/HIF Prolyl-hydroxylase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number159915-87-4
-
Formula Weight453.583
-
Molecular FormulaC26H35N3O4
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(Z)-2-(2-((4-((E)-1-(butoxyimino)propyl)-2,5-dimethylphenoxy)methyl)phenyl)-2-(methoxyimino)-N-methylacetamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Lin X, et al. Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):174-9.
molnova catalog
related products
-
HIF-1α-IN-2
HIF-1α-IN-2 is a novel and highly potent HIF-1α inhibitor with anticancer and antitumor activity that inhibits the expression of HIF-1α and VEGF in a dose-dependent manner and inhibits cell migration.
-
Arylsulfonamide 64B
Arylsulfonamide 64B (HIF inhibitor 64B) is a small molecule HIF pathway inhibitor.
-
Roxadustat
Roxadustat (FG4592, FG-4592) is a potent, orally available HIF prolyl hydroxylase (HIF-PHD) with IC50 of 591.4 nM.
