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G6PDi-1
CAS No. ——
G6PDi-1( —— )
Catalog No. M22375 CAS No. ——
G6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 10MG | 1147 | In Stock |
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| 25MG | 1696 | In Stock |
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| 50MG | Get Quote | In Stock |
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Biological Information
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Product NameG6PDi-1
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NoteResearch use only, not for human use.
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Brief DescriptionG6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?
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DescriptionG6PDi-1 is an effective G6PD inhibitor. It depletes NADPH and decreases inflammatory cytokine production. G6PDi-1 effectively inhibits G6PD.?Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes.?In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production.?In neutrophils, it suppresses respiratory burst.?
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetDehydrogenase
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RecptorG6PD
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Research Area——
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Indication——
Chemical Information
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CAS Number——
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Formula Weight284.34
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Molecular FormulaC14H12N4OS
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C2CCCCc1nc(ncc12)Nc3cc(C#N)sc3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ghergurovich J M , Juan C. García-Caaveras, Wang J , et al. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway[J]. Nature Chemical Biology, 2020, 16(7):1-9.
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