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Home - Products - Metabolic Enzyme/Protease - Fatty Acid Synthase - FT113

FT113

CAS No. 1630808-89-7

FT113( —— )

Catalog No. M21632 CAS No. 1630808-89-7

FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 140 Get Quote
10MG 244 Get Quote
25MG 412 Get Quote
50MG 606 Get Quote
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Biological Information

  • Product Name
    FT113
  • Note
    Research use only, not for human use.
  • Brief Description
    FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.
  • Description
    FT113 is a novel potent inhibitor of fatty acid synthase (fasn IC50 : 213 nM)and exhibits anti-cancer activity.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Athymic nude mice bearing MV-411 cellsDosage:5, 25, or 50 mg/kg Administration:P.O., twice daily for 16 daysResult:Caused 32 % and 50% tumor growth inhibition at 25 and 50 mg/kg, respectively in mice.
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Fatty Acid Synthase
  • Recptor
    FAS
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1630808-89-7
  • Formula Weight
    409.41
  • Molecular Formula
    C22H20FN3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:62.5 mg/mL (152.66 mM; Need ultrasonic)
  • SMILES
    OC1(CC1)C(=O)N1CCN(CC1)C(=O)c1ccc(cc1)-c1nc2ccc(F)cc2o1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Martin MW et al. Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN). Bioorg Med Chem Lett. 2019 Apr 15;29(8):1001-1006.
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