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Evocalcet

CAS No. 870964-67-3

Evocalcet( KHK7580 )

Catalog No. M22494 CAS No. 870964-67-3

Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 63 In Stock
10MG 96 In Stock
25MG 194 In Stock
50MG 309 In Stock
100MG 447 In Stock
500MG 972 In Stock
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Biological Information

  • Product Name
    Evocalcet
  • Note
    Research use only, not for human use.
  • Brief Description
    Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).
  • Description
    Evocalcet has an activating effect on the calcium-sensing receptor (CaSR).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Sprague Dawley chronic kidney disease (CKD) rats with adenine induced secondary hyperparathyroidism (SHPT)Dosage:0.03 and 0.3 mg/kg Administration:Oral Administration; 0.03 and 0.3 mg/kg, once Result:Decreased the serum PTH and Ca levels at a dose of 0.3 mg/kg.
  • Synonyms
    KHK7580
  • Pathway
    GPCR/G Protein
  • Target
    CaSR
  • Recptor
    CaSR
  • Research Area
    Cancer
  • Indication
    Parathyroid CarcinomaPrimary Hyperparathyroidism

Chemical Information

  • CAS Number
    870964-67-3
  • Formula Weight
    374.48
  • Molecular Formula
    C24H26N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:30 mg/mL (80.11 mM; Need ultrasonic and warming)
  • SMILES
    C[C@@H](N[C@H]1CCN(C1)c1ccc(CC(O)=O)cc1)c1cccc2ccccc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tanimura, Shinji, et al. Pharmaceutical composition containing aryl alkyl amine compound. WO 2017061621 A1.
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