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Enbezotinib
CAS No. 2359649-81-1
Enbezotinib( —— )
Catalog No. M35628 CAS No. 2359649-81-1
Enbezotinib is an inhibitor of RET autophosphorylation and can be used in cancer research.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 192 | In Stock |
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| 5MG | 169 | In Stock |
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| 10MG | 267 | In Stock |
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| 25MG | 438 | In Stock |
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| 50MG | 586 | In Stock |
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| 100MG | 770 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameEnbezotinib
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NoteResearch use only, not for human use.
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Brief DescriptionEnbezotinib is an inhibitor of RET autophosphorylation and can be used in cancer research.
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DescriptionEnbezotinib, an inhibitor of RET, can inhibit the RET autophosphorylation. Enbezotinib can be used for the research of cancer.
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In VitroEnbezotinib (compound 5) (0.3-300 nM) inhibits p-RET (y905) in RET-driven cells.
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In VivoEnbezotinib (compound 5) (2-5 mg/kg; twice daily for 27 days) decreases tumor size in mice.
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Synonyms——
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PathwayTyrosine Kinase
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Targetc-RET
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Recptorc-RET
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Research Area——
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Indication——
Chemical Information
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CAS Number2359649-81-1
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Formula Weight424.43
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Molecular FormulaC21H21FN6O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (235.61 mM; Ultrasonic (<80°C)
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SMILES[H][C@]12CCC[C@@]1([H])N1Cc3cc(F)cnc3O[C@@H](C)CNC(=O)c3cnn4cc(O2)c1nc34
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. ROGERS EW, et, al. Macrocyclic compounds for treating disease. WO2019126121A1.
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