Cart
sales@molnova.com
RET-IN-3
CAS No. 2414374-53-9
RET-IN-3( —— )
Catalog No. M37651 CAS No. 2414374-53-9
RET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 144 | Get Quote |
|
| 5MG | 217 | Get Quote |
|
| 10MG | 345 | Get Quote |
|
| 25MG | 625 | Get Quote |
|
| 50MG | 984 | Get Quote |
|
| 100MG | 1485 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameRET-IN-3
-
NoteResearch use only, not for human use.
-
Brief DescriptionRET-IN-3 is a RETV804M kinase inhibitor with potential anticancer activity for the study of non-small cell lung cancer.
-
DescriptionRET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM.
-
In VitroRET-IN-3 exhibits 16 and 410 fold selectivity compared to wt-RET and KDR, respectively.
-
In Vivo——
-
Synonyms——
-
PathwayTyrosine Kinase
-
Targetc-RET
-
Recptorc-RET
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2414374-53-9
-
Formula Weight339.39
-
Molecular FormulaC18H21N5O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (294.65 mM; Ultrasonic )
-
SMILESCN(C)CCCNc1ccn2ncc(-c3ccc4OCOc4c3)c2n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505.?
molnova catalog
related products
-
DUN73423
DUN73423 (RET-IN-21) is a potent tyrosine kinase (RET) inhibitor with antitumour activity for the study of cancer.
-
Vepafestinib
Vepafestinib is a RET inhibitor with potential antineoplastic activity.
-
4-methyl-2-(4-(trifl...
4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid is a metabolite of GW 501516.
