Compound 1769-24-0

CAS No. 1769-24-0

Compound 1769-24-0( —— )

Catalog No. M37931 CAS No. 1769-24-0

Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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200MG 26 In Stock
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Biological Information

  • Product Name
    Compound 1769-24-0
  • Note
    Research use only, not for human use.
  • Brief Description
    Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.
  • Description
    2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM.
  • In Vitro
    2-Methylquinazolin-4-ol inhibits ATCase in a concentration-dependent manner.
  • In Vivo
    2-Methylquinazolin-4-ol (0.2-1 mg; i.g.; for two days) inhibits ATCase in a dosedependent manner in vivo.Animal Model:Mice Dosage:0.2 mg, 0.4 mg, 0.6 mg, 0.8 mg, 1 mg Administration:Oral gavage, for two days Result:Showed an inhibitory effect upon ATCase.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1769-24-0
  • Formula Weight
    160.17
  • Molecular Formula
    C9H8N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (312.17 mM; Ultrasonic ) H2O : < 0.1 mg/mL (insoluble)
  • SMILES
    CC1=NC2=CC=CC=C2C(=O)N1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo). 1991 Jan;44(1):111-2.?
molnova catalog
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