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Casein kinase 1δ-IN-6
CAS No. 1579991-01-7
Casein kinase 1δ-IN-6( —— )
Catalog No. M36916 CAS No. 1579991-01-7
Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 196 | Get Quote |
|
| 5MG | 282 | Get Quote |
|
| 10MG | 424 | Get Quote |
|
| 25MG | 716 | Get Quote |
|
| 50MG | 1003 | Get Quote |
|
| 100MG | 1377 | Get Quote |
|
| 500MG | 2673 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCasein kinase 1δ-IN-6
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NoteResearch use only, not for human use.
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Brief DescriptionCasein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.
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DescriptionCasein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetCasein Kinase
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RecptorCasein Kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number1579991-01-7
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Formula Weight370.78
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Molecular FormulaC16H10ClF3N2OS
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Purity>98% (HPLC)
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Solubility——
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SMILESN(C(CC1=CC(Cl)=CC=C1)=O)C=2SC=3C(N2)=CC=C(C(F)(F)F)C3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.?
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