Casein kinase 1δ-IN-6

CAS No. 1579991-01-7

Casein kinase 1δ-IN-6( —— )

Catalog No. M36916 CAS No. 1579991-01-7

Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 196 Get Quote
5MG 282 Get Quote
10MG 424 Get Quote
25MG 716 Get Quote
50MG 1003 Get Quote
100MG 1377 Get Quote
500MG 2673 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Casein kinase 1δ-IN-6
  • Note
    Research use only, not for human use.
  • Brief Description
    Casein kinase 1δ-IN-6 is a potent and selective inhibitor of the protein kinase CK-1δ with an IC50 of 23 nM, demonstrating neuroprotective and anti-inflammatory activity in both in vitro and in vivo assays. Casein kinase 1δ-IN-6 can be used to study neurodegenerative diseases.
  • Description
    Casein kinase 1δ-IN-6 is a potent and selective protein kinase CK-1δ inhibitor with an IC50 of 23 nM. Casein kinase 1δ-IN-6 shows neuroprotective and anti-inflammatory properties both in vitro and in vivo. Casein kinase 1δ-IN-6 is a promising drug candidate and can be used for neurodegenerative diseases research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Casein Kinase
  • Recptor
    Casein Kinase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1579991-01-7
  • Formula Weight
    370.78
  • Molecular Formula
    C16H10ClF3N2OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(CC1=CC(Cl)=CC=C1)=O)C=2SC=3C(N2)=CC=C(C(F)(F)F)C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. José A Morales-Garcia, et al. Biological and Pharmacological Characterization of Benzothiazole-Based CK-1δ Inhibitors in Models of Parkinson's Disease. ACS Omega. 2017 Aug 31;2(8):5215-5220.?
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