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Bobcat339
CAS No. 2280037-51-4
Bobcat339( Bobcat 339 )
Catalog No. M13625 CAS No. 2280037-51-4
Bobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 42 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 147 | In Stock |
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| 50MG | 237 | In Stock |
|
| 100MG | 349 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameBobcat339
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NoteResearch use only, not for human use.
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Brief DescriptionBobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2).
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DescriptionBobcat339 (Bobcat 339) is a novel cytosine-based TET enzyme inhibitor with IC50 of 33 uM (TET1) and 73 uM (TET2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a; Bobcat339 is a useful tool for investigation of epigenetics and serve as a starting point for new therapeutics that target DNA methylation and gene transcription.
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In VitroBobcat339 (10 μM; 24 hours) significantly reduces global 5hmC levels by inhibiting TET enzyme function in HT-22 cells.
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In Vivo——
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SynonymsBobcat 339
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PathwayChromatin/Epigenetic
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TargetDNMT
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RecptorTET1|TET2
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Research Area——
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Indication——
Chemical Information
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CAS Number2280037-51-4
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Formula Weight297.742
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Molecular FormulaC16H12ClN3O
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Purity>98% (HPLC)
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SolubilityDMSO: Soluble （ < 1 mg/ml refers to the product slightly soluble or insoluble )
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SMILES——
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Chemical Name1-([1,1'-biphenyl]-3-yl)-4-amino-5-chloropyrimidin-2(1H)-one
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chua GNL, et al. ACS Med Chem Lett. 2019 Jan 31;10(2):180-185.
molnova catalog
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