JNJ-42253432
JNJ-42253432
Catalog No. M34298
JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels.
| Size | Price / USD | Stock | Quantity |
| 2MG | 179 | Get Quote |
|
| 5MG | 282 | Get Quote |
|
| 10MG | 426 | Get Quote |
|
| 25MG | 640 | Get Quote |
|
| 50MG | 861 | Get Quote |
|
| 100MG | 1116 | Get Quote |
|
| 500MG | 2277 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameJNJ-42253432
-
Brief Description
-
Description
-
Storage
-
NoteResearch use only, not for human use.
-
Reference1. Brian Lord, et al. Pharmacology of a novel central nervous system-penetrant P2X7 antagonist JNJ-42253432. J Pharmacol Exp Ther. 2014 Dec;351(3):628-41.?
molnova catalog
related products
-
Gefapixant
Gefapixant (AF-219, MK-7264) is an orally active, small molecule antagonist of P2X3-containing receptor with IC50 of 30 nM (hP2X3 homotrimer) and 100-250 nM (hP2X2/3 heterotrimer).
-
AZD-9056
A potent, selective, orally bioavailable P2X7 receptor antagonist; inhibits release of pro-inflammatory mediators from isolated human peripheral monocytes (IL-1β and IL-18) and human alveolar macrophages (IL-1β) with IC50 values of 10-13 nM.
-
Camlipixant
Camlipixant (BLU-5937) is an orally active purine P2X3 receptor antagonist that is potent, selective and competitive.
Cart
sales@molnova.com