Cart
sales@molnova.com
toralactone
CAS No. 41743-74-2
toralactone( —— )
Catalog No. M24380 CAS No. 41743-74-2
Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 239 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Nametoralactone
-
NoteResearch use only, not for human use.
-
Brief DescriptionToralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
-
DescriptionToralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism.
-
In VitroToralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity.
-
In Vivo——
-
Synonyms——
-
PathwayNuclear Receptor/Transcription Factor
-
TargetKeap1-Nrf2
-
RecptorNrf2
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number41743-74-2
-
Formula Weight272.25
-
Molecular FormulaC15H12O5
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 2.5 mg/mL (9.18 mM)
-
SMILESO=C1C2=C(O)C3=C(O)C=C(OC)C=C3C=C2C=C(C)O1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Salwa D. Alqahtani, et al. Abstract 1205: Rubrofusarin and toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity. AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC.
molnova catalog
related products
-
ML-385
A first-in-class small molecule inhibitor of NRF2 that binds to Neh1 DNA binding domain of NRF2 (IC50=1.9 uM) and inhibits the downstream target gene expression.
-
toralactone
Toralactone is a natural product isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism
-
Nrf2 activator-1
Nrf2 activator-1 is a potent activator of NF-E2-related factor 2 (Nrf2) and can be used to study COPD and other respiratory diseases, including asthma, acute lung injury (ALI), acute respiratory distress syndrome (ARDS), and pulmonary fibrosis.
