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rac-BHFF
CAS No. 123557-91-5
rac-BHFF( —— )
Catalog No. M17212 CAS No. 123557-91-5
Rac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 50 | In Stock |
|
| 10MG | 87 | In Stock |
|
| 25MG | 177 | In Stock |
|
| 50MG | 295 | In Stock |
|
| 100MG | 447 | In Stock |
|
| 500MG | 972 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Namerac-BHFF
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NoteResearch use only, not for human use.
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Brief DescriptionRac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively).
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DescriptionRac-BHFF is potent and selective GABA B receptor positive allosteric modulator that increases the potency and efficacy of GABA ( > 15-fold and > 149% respectively). It exhibits anxiolytic activity in vivo and is orally active.
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In Vitro——
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In Vivorac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice.rac-BHFF (3, 10, 30 and 100?mg/kg, p.o.) reverses SIH and high significance was reached for 100?mg?kg?1 (P<0.001). Animal Model:Male NMRI mice (20-25?g).Dosage:3, 10, 30 or 100 mg/kg.Administration:P.O..Result:Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3?mg/kg and above.
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Synonyms——
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PathwayApoptosis
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TargetPERK
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RecptorGABAB
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Research Area——
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Indication——
Chemical Information
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CAS Number123557-91-5
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Formula Weight330.34
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Molecular FormulaC17H21F3O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (302.72 mM)
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SMILESCC(C)(C)c1cc(c2c(c1)C(C(=O)O2)(C(F)(F)F)O)C(C)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Krishnamurthy S,et al.,Acta Crystallogr E Crystallogr Commun. 2015 Jul 1; 71(Pt 7): o449–o450.
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