antcin A

Research use only, not for human use.

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.

antcin A is a steroid-like phytochemical isolated from the fruiting bodies of a precious edible mushroom Antrodia cinnamomea with strong anti-inflammatory and anti-tumor effects.(In Vitro):Antcin A could significantly inhibit the occurrence of pyrolysis, decrease the expression of inflammatory factors, inhibit the activation and assembly of NLRP3 inflammasome, and significantly down-regulate the expression of NLRP3, Caspase-1 and GSDMD-NT in KCs.(In Vivo):In NAFLD mice, Antcin A could suppress the inflammatory response in liver tissues of mice, reduce lipid deposition, down-regulate the levels of ALT and AST, and improve liver function in mice. Antcin A could also inhibit the activation of NLRP3 inflammasome in liver tissue and decrease the level of inflammatory factors.

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NF-κB

NOD

NOD

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163597-24-8

454.64

C29H42O4

>98% (HPLC)

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C[C@H](CCC(C(C)C(O)=O)=C)[C@@H](CC1)[C@@](C)(C2)[C@@H]1C(CC[C@@H]([C@@H]1C)[C@]3(C)CCC1=O)=C3C2=O

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(-20℃)

With Ice Pack

≥ 2 years