CY-09

CAS No. 1073612-91-5

CY-09( NLRP3 inhibitor CY-09 )

Catalog No. M10304 CAS No. 1073612-91-5

CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 52 In Stock
5MG 65 In Stock
10MG 112 In Stock
25MG 235 In Stock
50MG 365 In Stock
100MG 548 In Stock
200MG Get Quote In Stock
500MG 1237 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    CY-09
  • Note
    Research use only, not for human use.
  • Brief Description
    CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor.
  • Description
    CY-09 (NLRP3 inhibitor CY-09) is a selective and direct NLRP3 inhibitor, binds to the ATP-binding motif of NLRP3 NACHT domain and inhibits NLRP3 ATPase activity; suppresses NLRP3 inflammasome assembly and activation, shows remarkable therapeutic effects on mouse models of cryopyrin-associated autoinflammatory syndrome (CAPS) and type 2 diabetes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    NLRP3 inhibitor CY-09
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NLRP3|NLRP3?inhibitor
  • Research Area
    Inflammation/Immunology
  • Indication
    ——

Chemical Information

  • CAS Number
    1073612-91-5
  • Formula Weight
    423.424
  • Molecular Formula
    C19H12F3NO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 77 mg/mL (181.8 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
  • SMILES
    O=C(O)C1=CC=C(/C=C(SC(N2CC3=CC=CC(C(F)(F)F)=C3)=S)\C2=O)C=C1
  • Chemical Name
    Benzoic acid, 4-[[4-oxo-2-thioxo-3-[[3-(trifluoromethyl)phenyl]methyl]-5-thiazolidinylidene]methyl]-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jiang H, et al. J Exp Med. 2017 Nov 6;214(11):3219-3238.
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