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Vesamicol hydrochloride
CAS No. 120447-62-3
Vesamicol hydrochloride( —— )
Catalog No. M33820 CAS No. 120447-62-3
Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 49 | Get Quote |
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| 10MG | 75 | Get Quote |
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| 25MG | 145 | Get Quote |
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| 50MG | 216 | Get Quote |
|
| 100MG | 312 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVesamicol hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionVesamicol hydrochloride ((±)-AH5183 hydrochloride) is a acetylcholine transport inhibitor.
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Description(±)-Vesamicol hydrochloride ((±)-AH5183 hydrochloride) is a potent vesicular acetylcholine transport inhibitor with a Ki of 2 nM. (±)-Vesamicol hydrochloride also displays high affinity for σ1 and σ2 receptors with Kis of 26 nM and 34 nM, respectively.
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In Vitro——
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In VivoAnimal Model:Male Wistar rats (120-300 g)Dosage:3 mg/kg Administration:Intraperitoneal injection; once Result:The levels of cytosolic acetylcholine (ACh) increased in all regions of the brain, while those of vesicular ACh decreased in all regions except for the striatum.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetAChR
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RecptorAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number120447-62-3
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Formula Weight295.85
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Molecular FormulaC17H26ClNO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 20.83 mg/mL (70.41 mM; Ultrasonic (<60°C)
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SMILESCl.OC1CCCCC1N1CCC(CC1)C1=CC=CC=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. S M Efange, et al. N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. J Med Chem. 1997 Nov 21;40(24):3905-14.?
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