Cart
sales@molnova.com
VU534
CAS No. 923509-20-0
VU534( —— )
Catalog No. M36972 CAS No. 923509-20-0
VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related to cardiometabolism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | In Stock |
|
| 5MG | 80 | In Stock |
|
| 10MG | 132 | In Stock |
|
| 25MG | 216 | In Stock |
|
| 50MG | 325 | In Stock |
|
| 100MG | 480 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVU534
-
NoteResearch use only, not for human use.
-
Brief DescriptionVU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related to cardiometabolism.
-
DescriptionVU534 is a NAPE-PLD activator, with an EC50 of 0.30 μM. VU534 is dual inhibitors of FAAH and sEH (IC50 of 1.2 μM). VU534 increases efferocytosis in a NAPE-PLD dependent manner. VU534 has the potential for cardiometabolic diseases study .
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMetabolic Enzyme/Protease
-
TargetFAAH
-
RecptorFAAH | Phospholipase | Epoxide Hydrolase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number923509-20-0
-
Formula Weight447.55
-
Molecular FormulaC21H22FN3O3S2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (55.86 mM; Ultrasonic )
-
SMILESCC1=CC2=C(SC(NC(=O)C3CCN(CC3)S(=O)(=O)C3=CC=C(F)C=C3)=N2)C(C)=C1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Jonah E Zarrow, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem. Biol. 2023, 18, 8, 1891–1904. ?
molnova catalog
related products
-
JNJ-42165279
JNJ-42165279 is a highly selective inhibitor of fatty acid amide hydrolase (FAAH) with IC50 of 70 nM for hFAAH.
-
Palmitoylisopropylam...
Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.
-
PF 750
PF 750 is a selective and covalent inhibitor of FAAH. PF 750 shows IC50s varying from 16.2 to 595 nM in different incubation times.
