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VU534
CAS No. 923509-20-0
VU534( —— )
Catalog No. M36972 CAS No. 923509-20-0
VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related to cardiometabolism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 55 | In Stock |
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| 5MG | 80 | In Stock |
|
| 10MG | 132 | In Stock |
|
| 25MG | 216 | In Stock |
|
| 50MG | 325 | In Stock |
|
| 100MG | 480 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVU534
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NoteResearch use only, not for human use.
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Brief DescriptionVU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases related to cardiometabolism.
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DescriptionVU534 is a NAPE-PLD activator, with an EC50 of 0.30 μM. VU534 is dual inhibitors of FAAH and sEH (IC50 of 1.2 μM). VU534 increases efferocytosis in a NAPE-PLD dependent manner. VU534 has the potential for cardiometabolic diseases study .
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetFAAH
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RecptorFAAH | Phospholipase | Epoxide Hydrolase
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Research Area——
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Indication——
Chemical Information
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CAS Number923509-20-0
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Formula Weight447.55
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Molecular FormulaC21H22FN3O3S2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (55.86 mM; Ultrasonic )
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SMILESCC1=CC2=C(SC(NC(=O)C3CCN(CC3)S(=O)(=O)C3=CC=C(F)C=C3)=N2)C(C)=C1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Jonah E Zarrow, et al. Small Molecule Activation of NAPE-PLD Enhances Efferocytosis by Macrophages. ACS Chem. Biol. 2023, 18, 8, 1891–1904. ?
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