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VU0238429
CAS No. 1160247-92-6
VU0238429( SCR-1481B1 )
Catalog No. M21562 CAS No. 1160247-92-6
VU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 35 | Get Quote |
|
| 5MG | 58 | Get Quote |
|
| 10MG | 102 | Get Quote |
|
| 25MG | 205 | Get Quote |
|
| 50MG | 288 | Get Quote |
|
| 100MG | 507 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameVU0238429
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NoteResearch use only, not for human use.
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Brief DescriptionVU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
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DescriptionVU0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5)( EC50 : 1.16 μM).
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In VitroVU 0238429 is positive allosteric modulator of mAChR5 (M5), with an EC50 of 1.16 μM, >30-fold selectivity versus M1 and M3, with no M2 or M4 potentiator activity.
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In Vivo——
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SynonymsSCR-1481B1
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorM5 mAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number1160247-92-6
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Formula Weight351.28
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Molecular FormulaC17H12F3NO4
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (427.01 mM)
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SMILESCOc1ccc(CN2C(=O)C(=O)c3cc(OC(F)(F)F)ccc23)cc1
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Chemical Name1-[(4-methoxyphenyl)methyl]-5-(trifluoromethoxy)-23-dihydro-1H-indole-23-dione
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Bridges TM et al. Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.
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