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Tiratricol

CAS No. 51-24-1

Tiratricol( Tiratricol | TRIAC | triiodothyroacetic acid. )

Catalog No. M14771 CAS No. 51-24-1

Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Tiratricol
  • Note
    Research use only, not for human use.
  • Brief Description
    Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.
  • Description
    Tiratricol (also known as TRIAC or triiodothyroacetic acid) is a thyroid hormone analogue.
  • In Vitro
    Western Blot Analysis Cell Line:Huh-7 cells Concentration:0.625, 2.5, 10, and 40 μM Incubation Time:24 h Result:Remarkably suppressed the viral proteins of NS1, NS2B, NS3, prM and capsid.
  • In Vivo
    Animal Model:C57BL/6 mice infected with YFV Dosage:0.2 mg/kg/day Administration:po; day 0–6 post infection (dpi) or from 2 days before infection to 6 dpi Result:Significantly reduce virus titers and protein expression.Restored body weight and improved the survival rate of YFV-infected mice by 40%.
  • Synonyms
    Tiratricol | TRIAC | triiodothyroacetic acid.
  • Pathway
    Endocrinology/Hormones
  • Target
    THR
  • Recptor
    Thyroid hormone
  • Research Area
    Endocrinology
  • Indication
    ——

Chemical Information

  • CAS Number
    51-24-1
  • Formula Weight
    621.93
  • Molecular Formula
    C14H9I3O4
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 100 mg/mL (160.78 mM); DMSO: 100 mg/mL (160.78 mM)
  • SMILES
    O=C(O)CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1
  • Chemical Name
    2-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)acetic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Carvalho GA, et al. Arq Bras Endocrinol Metabol, 2004, 48(1), 83-92.
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