Cart
sales@molnova.com
DS08210767
CAS No. 2376334-75-5
DS08210767( —— )
Catalog No. M32894 CAS No. 2376334-75-5
DS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 196 | Get Quote |
|
| 5MG | 306 | Get Quote |
|
| 10MG | 443 | Get Quote |
|
| 25MG | 638 | Get Quote |
|
| 50MG | 878 | Get Quote |
|
| 100MG | 1170 | Get Quote |
|
| 500MG | 2349 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDS08210767
-
NoteResearch use only, not for human use.
-
Brief DescriptionDS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with an IC50 of 90 nM.
-
DescriptionDS08210767 is a highly potent, orally bioavailable PTHR1 antagonist with IC50 of 90 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayEndocrinology/Hormones
-
TargetTHR
-
RecptorThyroid hormone receptor(THR)
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2376334-75-5
-
Formula Weight513.67
-
Molecular FormulaC31H39N5O2
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 5 mg/mL (9.73 mM; Ultrasonic (<80°C)
-
SMILESCC1(C)N=C(C2CCCCC2)c2ccc(cc2N(c2ccc(NCCNC3CCOCC3)cc2)C1=O)C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Arai Y, et al. Discovery of novel PTHR1 antagonists: Design, synthesis, and structure activity relationships. Bioorg Med Chem Lett. 2019 Sep 15;29(18):2613-2616.?
molnova catalog
related products
-
L-Thyroxine
L-Thyroxine(Levothyroxine) is an iodine containing hormone produced from thyroglobulin in the thyroid follicular cells.
-
Sobetirome
Sobetirome is a selective agonist of thyroid hormone receptor β (TRβ) and binds selectively to TRβ-1 (EC50: 0.16 μM).
-
NH-3
NH-3 is an orally active, reversible thyroid hormone receptor (THR) antagonist with an IC 50 of 55 nM. NH-3, a derivative of the selective thyromi-metic GC-1, inhibits binding of thyroid hormones to their receptor and that inhibits cofactor recruitment.
