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Telratolimod
CAS No. 1359993-59-1
Telratolimod( MEDI9197 | 3M-052 )
Catalog No. M26840 CAS No. 1359993-59-1
Telratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 223 | In Stock |
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| 5MG | 335 | In Stock |
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| 10MG | 500 | In Stock |
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| 25MG | 806 | In Stock |
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| 50MG | 1098 | In Stock |
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| 100MG | 1485 | In Stock |
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| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTelratolimod
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NoteResearch use only, not for human use.
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Brief DescriptionTelratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.
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DescriptionTelratolimod is a toll-like receptors 7/8 agonist. It has an antitumor activity.(In Vivo):Telratolimod (50 μg) suppresses the tumor volume and more effectively blocks tumor growth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs the survival of mice bearing large tumors .
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In VitroTelratolimod (3M-052) is a toll like receptors 7/8 (TLR7/8) agonist, with antitumor activity.
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In VivoTelratolimod (50 μg) inhibits the tumor volume, and more potently blocks tumor gowth in combination with CpG ODN in BALB/c mice bearing CT26 colon carcinoma cells. Telratolimod (100 μg) plus 200 μg of CpG ODN slows tumor growth and prolongs survival of mice bearing large tumors.
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SynonymsMEDI9197 | 3M-052
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PathwayImmunology/Inflammation
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TargetTLR
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RecptorLpxC
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Research Area——
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Indication——
Chemical Information
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CAS Number1359993-59-1
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Formula Weight593.901
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Molecular FormulaC36H59N5O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 62.5 mg/mL (105.24 mM)
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SMILESCCCCCCCCCCCCCCCCCC(=O)NCCCCOn1c(CCCC)nc2c(N)nc3ccccc3c12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ushiyama F, et al. Lead optimization of 2-hydroxymethyl imidazoles as non-hydroxamate LpxC inhibitors: Discovery of TP0586532. Bioorg Med Chem. 2021;30:115964.
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