Cart
sales@molnova.com
Afimetoran
CAS No. 2171019-55-7
Afimetoran( BMS-986256 )
Catalog No. M28229 CAS No. 2171019-55-7
Afimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 177 | Get Quote |
|
| 10MG | 295 | Get Quote |
|
| 25MG | 502 | Get Quote |
|
| 50MG | 709 | Get Quote |
|
| 100MG | 1008 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameAfimetoran
-
NoteResearch use only, not for human use.
-
Brief DescriptionAfimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
-
DescriptionAfimetoran is a toll-like receptor antagonist, which can be used in the research of inflammatory and autoimmune diseases.
-
In Vitro——
-
In Vivo——
-
SynonymsBMS-986256
-
PathwayImmunology/Inflammation
-
TargetTLR
-
Recptormitotic kinesin Kif18A
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2171019-55-7
-
Formula Weight444.57
-
Molecular FormulaC26H32N6O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (224.94 mM)
-
SMILESCC(C)c1c(-c2cn3ncnc3c(C)c2C)[nH]c2c1cc(C1CCN(CC(N)=O)CC1)cc2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Tamayo NA, et al. Targeting the Mitotic Kinesin KIF18A in Chromosomally Unstable Cancers: Hit Optimization Toward an In Vivo Chemical Probe. J Med Chem. 2022;65(6):4972-4990.
molnova catalog
related products
-
ODN 1826
ODN 1826 is a 20-mer DNA strand, a TLR9 agonist and an immunostimulant, with anti-tumor and cardioprotective effects, promoting apoptosis, and stimulating the production of NO and iNOS. ODN 1826 is a CpG DNA mimetic that can be used as an adjuvant for synthetic vaccines.
-
Chloranil
Chloranil (tetrachloro-p-benzoquinone) triggers inflammation and neurological dysfunction through Toll-like receptor 4 signaling and can be used to model inflammation in mice.
-
BMS-905
BMS-905 is a potent dual inhibitors of TLR7 and TLR8 with good selectivity against TLR9 and other family members. BMS-905 can be used in studies about the treatment of diseases such as psoriasis, arthritis, and lupus.
