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TIQ-15
CAS No. 1380336-17-3
TIQ-15( TIQ-15 | TIQ 15 | TIQ15 )
Catalog No. M11572 CAS No. 1380336-17-3
TIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1053 | Get Quote |
|
| 50MG | 2142 | Get Quote |
|
| 100MG | 2790 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameTIQ-15
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NoteResearch use only, not for human use.
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Brief DescriptionTIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM.
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DescriptionTIQ-15 is a potent and selective CXCR4 antagonist, inhibits attachment of X4 HIV-1IIIB virus in MAGI-CCR5/CXCR4 cells with IC50 of 3 nM; inhibits calcium release in Chem-1 cells with IC50 of 3 nM, shows no cross-activity in a panel of chemokine receptor assays in both CXCR and CCR types.
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In Vitro——
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In Vivo——
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SynonymsTIQ-15 | TIQ 15 | TIQ15
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1380336-17-3
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Formula Weight364.537
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Molecular FormulaC23H32N4
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Purity>98% (HPLC)
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Solubility——
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SMILESNCCCCN(C[C@H]1CC2=C(C=CC=C2)CN1)[C@@H]3C4=NC=CC=C4CCC3
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Chemical NameN1-(((R)-1,2,3,4-tetrahydroisoquinolin-3-yl)methyl)-N1-((S)-5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Truax VM, et al. ACS Med Chem Lett. 2013 Sep 5;4(11):1025-30.
2. Yesim A. Tahirovic, et al. ACS Med. Chem. Lett., 2018, 9 (5), pp 446-451.
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