Suprafenacine( N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide )

Catalog No. M27928 CAS No. 1477482-50-0

Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase.

Purity : >98% (HPLC)

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10MG	282	Get Quote
25MG	507	Get Quote
50MG	712	Get Quote
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Biological Information

Product Name

Suprafenacine
Note

Research use only, not for human use.
Brief Description

Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase.
Description

Suprafenacine is a cell-permeable microtubule destabilizer that induces cell cycle arrest and apoptosis in G2/M phase. Suprafenacine binds to microtubules and inhibits aggregation at the colchicine junction. Suprafenacine is selective for cancer cells, including drug-resistant cancer cells.
In Vitro

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In Vivo

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Synonyms

N'-[(E)-(4-methylphenyl)methylidene]-4,5,6,7-tetrahydro-1H-indazole-3-carbohydrazide
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

Microtubule/Tubulin
Recptor

β2-adrenergic receptor
Research Area

——
Indication

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Chemical Information

CAS Number

1477482-50-0
Formula Weight

282.347
Molecular Formula

C16H18N4O
Purity

>98% (HPLC)
Solubility

——
SMILES

Cc1ccc(\C=N\NC(=O)c2n[nH]c3CCCCc23)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Shuyun Bi, et al. Study on the interactions of mapenterol with serum albumins using multi-spectroscopy and molecular docking. Luminescence. 2016 Mar;31(2):372-379.

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