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Sulforaphene

CAS No. 592-95-0

Sulforaphene( —— )

Catalog No. M21772 CAS No. 592-95-0

Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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5MG 65 In Stock
10MG 110 In Stock
25MG 215 In Stock
50MG 320 In Stock
100MG 474 In Stock
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Biological Information

  • Product Name
    Sulforaphene
  • Note
    Research use only, not for human use.
  • Brief Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M.
  • Description
    Sulforaphene, isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10-4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EGFR, p-ERK1/2, NF‐κB and other signals.
  • In Vitro
    Western Blot Analysis Cell Line:HepG2 and Hep3B cell Concentration:0-40 μM Incubation Time:48 h Result:Increased Bax expression and reduced Bcl-2 expression.Inhibited expression of NF-??B-dependent genes (COX-2, iNos, and cyclinD1).
  • In Vivo
    Animal Model:Mouse HCT116 xenograft model Dosage:1 and 5 mg/kg Administration:i.p., everyday Result:Inhibited tumor growth, and increased CDK1, MK2, and p38 phosphorylation.
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    592-95-0
  • Formula Weight
    175.27
  • Molecular Formula
    O=S(/C=C/CCN=C=S)C
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO : 100 mg/mL (570.55 mM; Need ultrasonic)
  • SMILES
    O=S(/C=C/CCN=C=S)C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kuang P, et al. Separation and purification of sulforaphene from radish seeds using macroporous resin and preparative high-performance liquid chromatography. Food Chem. 2013 Jan 15;136(2):342-7. 2. Anita M. Brinker, et al. Herbicidal activity of sulforaphene from stock (Matthiola incana). Journal of Chemical Ecology. Vol. 19. No. 10, 1993. 3. Mondal A, et al. Sulforaphene promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation. General Physiology and Biophysics, 27 Nov 2015, 35(1):25-34.
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