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Selnoflast

CAS No. 2260969-36-4

Selnoflast( —— )

Catalog No. M35589 CAS No. 2260969-36-4

Selnoflast (example 6) is a NLRP3 inhibitor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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2MG 201 Get Quote
5MG 306 Get Quote
10MG 511 Get Quote
25MG 908 Get Quote
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Biological Information

  • Product Name
    Selnoflast
  • Note
    Research use only, not for human use.
  • Brief Description
    Selnoflast (example 6) is a NLRP3 inhibitor.
  • Description
    Selnoflast (RO-7486967) Formerly known as Somalix/RG6418/IZD334, Selnoflast is an orally available inhibitor of NLRP3. Selnoflast is used in research into systemic inflammation, such as ulcerative colitis and chronic obstructive pulmonary disease.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    NF-κB
  • Target
    NOD
  • Recptor
    NOD
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2260969-36-4
  • Formula Weight
    391.53
  • Molecular Formula
    C20H29N3O3S
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 5 mg/mL (12.77 mM; ultrasonic and adjust pH to 8 with 1M NaOH ) 1M NaOH : 3.33 mg/mL (8.51 mM; adjust pH to 12 with 1M NaOH)
  • SMILES
    CCN1CCC(CC1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2CCCc12
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Vande Walle L, et al. Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets. Nat Rev Drug Discov. 2023 Nov 29.?
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